John Marshall, Ph.D.
Dr. Marshall, Ph.D., is a leading expert in protein biochemistry and biophysics,
and has developed sophisticated biochemical and biophysical techniques
and methods for protein identification and quantification. Dr. Marshall has published numerous papers on the development of reproducible chromatographic
and electrophoretic methods for the identification of proteins and biomarkers from blood, and on the large-scale identification of proteins and polypeptides
from fluids or tissue using mass spectrometry. Dr. Marshall has applied eukaryotic cell culture, cellular transfection and scanning laser fluorescence microscopy
for the quantification protein expression and the assembly of membrane protein complexes using laser confocal microscopy.
Dr. Marshall has served as a group leader in proteomics and cell biology in a private biomarker company that isolated new molecules using mass spectrometry,
and created new antibodies and immunoassays against the markers leading
to 12 patents approved thus far and a total of 65 patent applications. These patents also include novel computer algorithms for detecting biomarkers, and Dr. Marshall continues to design and assemble novel computer algorithms, computer platforms and rigorous statistical tests to detect biomarkers. At present, he is overseeing
the creation of a PC/Windows-based set of applications to find and manage proteomic biomarker data using the C++ object language and SQL data.